Garrison Keillor’s popular public radio show “A Prairie Home Companion” is coming back to the big screen live in HD at the Strand Theatre, 345 Main St., Thursday, Oct. 21 at 8 p.m.

The all-new live show will originate from the famed Fitzgerald Theater in St. Paul, Minn., where the show has been performed since 1974. The performance will feature the boot-stompin’, heart-breakin’ songs of Old Crow Medicine Show, the sweet sounds of Nickel Creek’s Sara Watkins, some smoldering honky-tonk from Joe Ely and soulful duets with singer/songwriter Andra Suchy.

Also joining the show will be The Royal Academy of Radio Actors — Sue Scott, Tim Russell and both sound effects wizards, Tom Keith and Fred Newman — plus a The Guy’s All-Star Shoe Band and “The News from Lake Wobegon.” Audiences will enjoy two hours of non-stop fun on the big screen.

Each week, “A Prairie Home Companion” is heard by more than four million listeners of every age on more than 600 public radio stations across the country. The show, performed live on stage in front of an audience, features comedy sketches, music and Keillor’s signature monologue. “A Prairie Home Companion” has been host to thousands of guest artists and has been broadcast from Canada, Ireland, Scotland, England, Germany, Iceland and nearly each of America’s 50 states.

Tickets are $20, $10 for students, and seating is general admission. Tickets are available by calling the Strand at 594-0070; at the Box Office Window daily from 6:30 to 8:30 p.m. or online at rocklandstrand.com.

VillageSoup Art/Entertainment Editor Dagney Ernest can be reached at 207-594-4401 or by e-mail to dernest@villagesoup.com.